the Hunt for Truth

Strength Through Pathogenesis
and Pathophysiology of Depression

by Reigh Simuzoshya


Scientists have been searching for more evidence with regard to pathogenesis and pathophysiology of depression and the resultant neurobiological effects thereof. But the elucidation of the underlying pathophysiology of this condition continues to be elusive. Some theories claim that depression is linked to a dysfunction of the dopaminergic and GABA-ergic system. Others assert that it is associated with a deficit of norepinephrine and serotonin exacerbated by an alteration in the expression of neuropeptides. Yet another theory claims that the overdrive of the hypothalamic-pituitary adrenal system is another risk factor for depression.

Chances are that a combination of all these factors can certainly intensify the onset of depression.

Grace by Nathan Furr free photo #12440Depression can be draining. It can take away your energy, dampen your hopes for the future and your drive. It even cripples the desire to do what is needed to feel better. Scientists…

View original post 564 more words